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Presentation Title

Adolescent exposure to CB1 receptor agonist elicits a disinhibited PFC state in adulthood.

Student Presenter(s) and Advisor

Chanalee Hocharoen '13Follow

Location

Library 205

Abstract

Adolescence is a developmental period associated with risky behaviors. The prefrontal cortex (PFC) develops during adolescence and risky behaviors like drug use can alter patterns of development. Although the drive for PFC development can be interrupted through many pathways, little is known about the effects of cannibis exposure on adolescent brain development. To further understand the endocannabinoid system’s role in development, effects of adolescent exposure to CB1 receptor agonist WIN on PFC development was examined. Results imply that a disinhibited PFC in adulthood may be, in part, a result of altered drive for neural development during adolescence.

Presentation Type

Individual Presentation

Start Date

4-9-2013 10:00 AM

End Date

4-9-2013 10:20 AM

Panel

Panel: Memory, Meaning and Choice

Panel Moderator

Jean-Luc Garneau

Field of Study for Presentation

Biology

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Apr 9th, 10:00 AM Apr 9th, 10:20 AM

Adolescent exposure to CB1 receptor agonist elicits a disinhibited PFC state in adulthood.

Library 205

Adolescence is a developmental period associated with risky behaviors. The prefrontal cortex (PFC) develops during adolescence and risky behaviors like drug use can alter patterns of development. Although the drive for PFC development can be interrupted through many pathways, little is known about the effects of cannibis exposure on adolescent brain development. To further understand the endocannabinoid system’s role in development, effects of adolescent exposure to CB1 receptor agonist WIN on PFC development was examined. Results imply that a disinhibited PFC in adulthood may be, in part, a result of altered drive for neural development during adolescence.