•  
  •  
 

Eukaryon

Class Year

2009

Abstract

Several lines of research on human and rodent subjects have demonstrated that early-life stress results in multiple negative outcomes, including increased incidence of psychopathologies. The current study sought to further the research on adolescent versus adult rats on anxiety-like reactions to chronic stress. The purpose of the current study was to assess whether 7 days of chronic restraint stress (20 minutes/day) results in higher anxiety-like profiles on the elevated plus maze and increased stress-induced neuroendocrine adaptations in adolescent versus adult rats. This type of research is critical for the prevention and treatment of psychopathologies stemming from early-life stress/maltreatment. There were no significant differences in anxiety-like behavior on the elevated plus maze or between age groups on neuroendocrine measures of stress. However, non-significant trends were observed in the anticipated directions, such that adolescent stressed rats spent less time on the open arms of the elevated plus maze. Implications and suggestions for future research are discussed.

Disclaimer

Eukaryon is published by students at Lake Forest College, who are solely responsible for its content. The views expressed in Eukaryon do not necessarily reflect those of the College. Articles published within Eukaryon should not be cited in bibliographies. Material contained herein should be treated as personal communication and should be cited as such only with the consent of the author.

Share

COinS