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Presentation Title
Applying a Novel Telomere-anchored PCR assay to a New Organism
Location
Durand Art Institute, 2nd Floor Balcony
Abstract
Telomeres are nucleoprotein complexes that protect the ends of eukaryotic chromosomes. During DNA replication, chromosomes cannot be completely copied, causing telomeres to shorten over time. Shortened telomeres are characteristic in cellular abnormalities such as cancer. However, the enzyme telomerase lengthens telomeres to prevent crucial genetic material from being removed. In our lab, we use the model organism, Aspergillus nidulans, because of its short, highly regulated telomeres. Our lab developed a telomere-anchored PCR-assay to measure telomere length in A. nidulans. This semester, I am determining if this assay can be applied to other organisms, starting with A. oryzae.
Presentation Type
Restricted Poster: Campus only access
Start Date
4-8-2014 2:40 PM
End Date
4-8-2014 4:00 PM
Panel
Posters: The Ken Weik Poster Session
Field of Study for Presentation
Biology
Applying a Novel Telomere-anchored PCR assay to a New Organism
Durand Art Institute, 2nd Floor Balcony
Telomeres are nucleoprotein complexes that protect the ends of eukaryotic chromosomes. During DNA replication, chromosomes cannot be completely copied, causing telomeres to shorten over time. Shortened telomeres are characteristic in cellular abnormalities such as cancer. However, the enzyme telomerase lengthens telomeres to prevent crucial genetic material from being removed. In our lab, we use the model organism, Aspergillus nidulans, because of its short, highly regulated telomeres. Our lab developed a telomere-anchored PCR-assay to measure telomere length in A. nidulans. This semester, I am determining if this assay can be applied to other organisms, starting with A. oryzae.