2019 - 22nd Annual Steven Galovich Memorial Student Symposium

Presentation Title

Effects of Prolonged Social Isolation: Sex Differences in Anxiety, Depression, and Sociability Behavior in Male and Female Rats

Student Presenter(s) and Advisor

Eliska Mrackova, Lake Forest CollegeFollow

Department or Major

1: Art History & Neuorscience

2: Cellular & Molecular Pharmacology

Location

Lillard Lobby

Abstract

Clinically, prolonged social isolation in adolescence is regarded as a risk factor for the development of anxiety. The purpose of this research project was to determine whether the duration of social isolation, sex of the animal, or the housing condition would affect the development of depressive-like behaviors. Overall, the data from open field, conditioned place preference, appetitive conditioning, and social-interaction tests revealed that prolonged social isolation affected sociability behavior and increased anxiety behavior. Future research will focus on determining possible sex differences in the basolateral amygdala using the deltaFosB marker for chronic stress neuronal activation.

Presentation Type

Poster

Start Date

4-9-2019 1:00 PM

End Date

4-9-2019 2:15 PM

Panel

Poster Session

Field of Study for Presentation

Neuroscience

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Apr 9th, 1:00 PM Apr 9th, 2:15 PM

Effects of Prolonged Social Isolation: Sex Differences in Anxiety, Depression, and Sociability Behavior in Male and Female Rats

Lillard Lobby

Clinically, prolonged social isolation in adolescence is regarded as a risk factor for the development of anxiety. The purpose of this research project was to determine whether the duration of social isolation, sex of the animal, or the housing condition would affect the development of depressive-like behaviors. Overall, the data from open field, conditioned place preference, appetitive conditioning, and social-interaction tests revealed that prolonged social isolation affected sociability behavior and increased anxiety behavior. Future research will focus on determining possible sex differences in the basolateral amygdala using the deltaFosB marker for chronic stress neuronal activation.