Bachelor of Arts (BA)
Department or Program
Matthew R. Kelley
Jeremy Amiel Rosenkranz
Clinically, prolonged social isolation in adolescence is regarded as a risk factor for the development of anxiety. The purpose of this research project was to determine whether the duration of social isolation, sex of the animal, or the housing condition would affect the development of depressive-like behaviors. Overall, the data from open field, conditioned place preference, appetitive conditioning, and social interaction tests revealed that prolonged social isolation affected the sociability behavior as well as increased the anxiety behavior. Future research will focus on determining possible sex differences in the Basolateral Amygdala using the deltaFosB marker for chronic stress neuronal activation.
Mrackova, Eliska, "Effects of Prolonged Social Isolation: Sex Differences in Anxiety, Depression, and Sociability Behavior in Male and Female Rats" (2019). Senior Theses.
Available for download on Saturday, May 04, 2024