Class Year

2019

Date

4-14-2019

Document Type

Thesis

Distinguished Thesis

Yes

Degree Name

Bachelor of Arts (BA)

Department or Program

Neuroscience

First Advisor

Matthew R. Kelley

Second Advisor

Jeremy Amiel Rosenkranz

Third Advisor

Rebecca Goldberg

Abstract

Clinically, prolonged social isolation in adolescence is regarded as a risk factor for the development of anxiety. The purpose of this research project was to determine whether the duration of social isolation, sex of the animal, or the housing condition would affect the development of depressive-like behaviors. Overall, the data from open field, conditioned place preference, appetitive conditioning, and social interaction tests revealed that prolonged social isolation affected the sociability behavior as well as increased the anxiety behavior. Future research will focus on determining possible sex differences in the Basolateral Amygdala using the deltaFosB marker for chronic stress neuronal activation.

Language

English

Comments

Phi Beta Kappa thesis award, co-winner

Available for download on Saturday, May 04, 2024


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